Pharma
Solutions for pharmaceutical industry.
Pharmaceutical Industry cGMP guidelines are an integral part of Kinematica compliance with the highest of the world’s regulatory standards. Complete safety to ensure low-risk product manufacturing in sterile environments as well, is part of Kinematica’s long-lasting experience in supplying specialized solutions to the largest pharmaceutical companies around the world. Comprehensive expertise for seamless integration with quality control and other specialized clean-room systems can also be offered.
BENEFITS: EXECUTIVE OVERVIEW
- Highest results reproducibility for an extremely narrow particle size distribution in accordance to the most demanding specifications
- Fully controlled homogenizing with industry-leading shear rates of up to 300 000 s-1
- Full CIP / SIP compliance and comprehensive certification in accordance to the widest acknowledged standards by including highest class clean-room for complete sterile environments and zero-contamination
Adjuvant Emulsion
In times of corona virus leading the world’s main topic, vaccine development is on everyone’s lips. Vaccines are used to provoke an immune response of the body by the production of antibodies through antigens. Adjuvant can be added to the vaccines for an improved immune response for a boost of antibody production and thus, a reduced number of antigens is required. There are
different types of adjuvants. Depot types of adjuvant act as depot for the antigen. It results in a longer exposure of the antigen to trigger a maximized immune response. Here, the adjuvants are based on emulsion, liposomes or microparticles, which act as a carrier for the antigen. The carrier efficiency is, amongst others, defined by the surface of the carrier. Therefore, the smaller the carrier, the better. Sub-micronized or nano-dispersed emulsions are desired. Kinematica can provide equipment for dispersions down to nano-scale using technologies with highest dispersion efficiency for production or batch production. We have experience in the field of micro-encapsulation, liposome production and nano-emulsions for sterile vaccine applications.
